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Bioactivity studies and Activity guided separation of anti-inflammatory compounds from Alpinia calcarata rhizome and leaf

NRC Grant: 12-081

Dr. S. Chelvendran
Industrial Technology Institute
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Area of Research: Medical Sceince
Status: Ongoing

 

Objectives

  1. a) To collect the plant material, extract and screen for bioactivity by using anti-inflammatory assays: Chemiluminescence assay (ROS whole blood and COX inhibitory assays) and NO inhibitory assay. b) To fractionate active extracts and screen the fractions for Chemiluminescence (ROS whole blood and COX inhibitory assays) and NO inhibitory assay to isolate COX and NO inhibitors of A. calcarata. c) To characterize COX and NO inhibitors of A. calcarata. d) To prepare an anti-inflammatory formulation from the active fractions and the isolated compounds of A. calcarata for further studies towards drug development.

 

 

You are here: Home Grants - 2012 Bioactivity studies and Activity guided separation of anti-inflammatory compounds from Alpinia calcarata rhizome and leaf