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Development of a natural gastroprotective agent from Trichosanthes cucumerina Linn

NRC Grant: 12-023

Dr. L.D.A.M. Arawwawala
Industrial Technology Institute
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Area of Research: Medical Sceince
Status: Ongoing

 

Objectives

  1. a) Sequentially fractionate a hot water extract of T. cucumerina. b) Identify the active fraction/s that responsible for gastroprotective activity c) Identify possible mechanism/s by which the active fraction/s mediates gastoprotective activity, in vitro and in vivo, by evaluating effects on (a) acidity and volume of gastric juice (b) mucus content of stomach (c) antihistamine activity (d) antioxidant activity (e) anti Helicobacter pylori activity d) Evaluate toxic potential (acute and chronic toxicity) of the active fraction/s responsible for gastroprotective activity e) Identify the active fraction, possible compound/s responsible for gastoprotective activity f) Develop a marketable value added product from T. cucumerina for treatment of gastric ulcers

 

 

You are here: Home Grants - 2012 Development of a natural gastroprotective agent from Trichosanthes cucumerina Linn