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Effect of the presence of gamete/Embryo on the modulation of secretory proteome in the cow: Alteration by the heat stress

11-198
Principal Investigator
PI
Prof. M. P. B. Wijayagunwardena

Department of Animal Science, University of Peradeniya

Overview

The aim of the proposed study is to determine the role of gametes/embryo on the modulation of the oviductal proteome, as well as the effect of heat stress on those changes. In vitro and in vitro experiments experimental heat stress/shock will be created and altered oviductal secretory protein profile will be examined using 2-D Gel electrophoresis, image analysis and quantitation The data will give rise to a better understanding of the local modulation of oviductal proteome and identify the factors, whose alteration by heat stress negatively effects gamete transport, fertilization and early embryonic development in the oviduct. Understanding of the basic mechanisms will also allow us to overcome the problem of compromised fertilization under the heat stress. Consequently, the knowledge gained can be used efficiently to improve the fertility in the livestock, and therefore may improve the socioeconomic status of the farmers in developing countries including Sri Lanka by increasing the production of offspring and milk and thus the profit.

 

 

You are here: Home Grants - 2012 Effect of the presence of gamete/Embryo on the modulation of secretory proteome in the cow: Alteration by the heat stress